Please read #18 of Malwarebytes' FAQ Common Issues, Questions, and their Solutions where it states:
'ISSUE: I keep getting the following detections, even after allowing Malwarebytes' Anti-Malware to fix them:
HKEY_CLASSES_ROOT\scrfile\shell\open\command\(default) (Broken.OpenCommand) -> Bad: (NOTEPAD.EXE %1) Good: ("%1" /S)
HKEY_CLASSES_ROOT\regfile\shell\open\command\(default) (Broken.OpenCommand) -> Bad: (NOTEPAD.EXE %1) Good: (regedit.exe "%1")
SOLUTION: Most often when these two items return repeatedly it is due to the presence of an IOLO product such as System Mechanic. System Mechanic and other IOLO security products alter these settings from their Windows defaults. If you do have an IOLO product installed, it is best to simply change the security setting in your IOLO product so that it does not change the settings for .reg files and .scr files or that you simply have Malwarebytes' Anti-Malware ignore these particular detections. These entries are not actual infections, just system settings changes that are not set to their defaults, which is something that some infections will do to prevent .reg files and .scr files from executing, which is why Malwarebytes' Anti-Malware detects these items, since it has no way of knowing if the change was made by the user, an infection, or a legitimate software such as IOLO.'
I would strongly suggest against using System Mechanic, or any registry cleaners (or optimizers) for that matter. You will read throughout the forums, "they have been known to create more problems then they fix".
Best of luck..