Followed the tried and true method..made a full image
back of my C partition, then uninstalled Office 2007, Adobe Acrobat 7 Pro...rebooted.
Installed Office 2010 Pro and Adobe Acrobat X Pro ....downloaded and ran the updates followed by another image backup.
Went without any hiccups ...even Outlook started backup, reconnected with the mail messages on my D: drive and sent/received messages.
Boring, uneventful...and successful.
Thanks and hope this helps.