Quck question deserves a quick answer
And that answer is no, there are no safe software utilities for the registry.
The regulars in these forums always say that using registry cleaners, registry optimizers, registry defraggers, and "System Optimizers" is not needed and can be very dangerous.
The registry doesn't need any of those things and claims to the contrary are never considered.
Performance problems can often be solved step by step, but clues would be needed so any diagnosing can begin.
I don't think this Webware forum is the place to do that.