RE: How do you run msconfig/startup?
Within one question you have really asked MANY.
First off, there are a myriad of things that can cause computers to run slowly.
When was the last time you cleaned out all of your unnecessary files like those in your Cache, cookies, history, etc? These only take up space and slow the process of the reading of your hard drive in addition to the assistance of posing threats of different types of mal-ware.
Which brings up the NEXT item. Do you know of any mal-ware hiding on your computer. Some mal-wares can put a complete stop to your computer!
Do you have programs on your computer that you have downloaded and installed yourself that you do not use any more? If you have NON-MS software that you don't use any more it just takes up disk space, therefore, slowing the reading process of your hard drive even further. If you delete any of these programs do you know how to find files they may leave behind? Yes, some programs DO leave files behind when you delete the program. These can add up over time and slow the process of reading your hard drive.
When was the last time you ran ScanDisk? Bad sectors can possibly reek havoc on your system. In the unusual event that you may find bad sectors, a repair tech can retrieve them for you.
When was the last time you Defragged? Fragmented files can REALLY slow down your computer! Since you don't know about the msconfig/startup thing I'll tell you (LATER) how to get there so you can shut off everything there before Defragging. Those running programs in there can only fragment WORSE if you defrag with them running. This is the ONLY time you will want to turn off your anti-malware progs. Since they will not be running you will want to disconnect from the internet while they are off and the system is defragging. I, personally, like to disconnect from the net (I'm on Cable ISP) then turn off those progs in msconfig, then run ScanDisk, then Defrag, then set ScanDisk to run again, then turn on the progs I want...like my Anti-malware stuff and finally reboot my computer. This helps MY computer a LOT!!!
If you've never Defragged this may take a LONG time so do it when you don't need to be on your computer for a WHILE.
What software are you running? Could it be that you have some software Conflicts somewhere? For instance, are you running two firewalls at once?
NOW, to address the msconfig/startup thing:
1. Click on 'start'.
2. At the bottom of the 'panel' that comes up click ''Run...''
3. In the small window that then comes up type '' msconfig '' and click ''OK''.
4. In the ''System Configuration Utility'' window that pops up click on the ''Startup'' Tab.
5. In the list you will see, UNcheck ALL boxes to programs you do not want running constantly. This includes Instant Messaging software. Be sure to leave all of your Anti-Virus, other Anti-Malware programs and any others you WANT (like a Weather program or non-MS Firewall) checked.
Note: You WILL still be able to use all of the programs you UNcheck. They just won't be running in the background eating up resources.
WARNING: If you don't know about contents of the other Tabs within the ''System Configuration Utility'', obviously, you make look but NOT touch! 
IF all of that doesn't help, you can learn about what you see in your Task Manager HERE:
http://downloads.techrepublic.com.com/5138-10877-5747817.html?tag=tr.dl.zdn&tag=nl.e530
If you do not have a Tech Republic Account, make one so you can download this PDF File. It tells you about what is safe/not safe to turn off within Windows and the ramifications of doing so. After reviewing that PDF very carefully you can deside if it's worth it [to you] to try to alter these particular settings.
I hope this helps you and doesn't confuse you any further. 
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