Clarification request: Not sure what you mean.
Computers, especially desktop computers, don't care what keyboard and mouse are connected or whether they are the same brand.
Is this a Desktop computer or a laptop? What make and model?
Are you sure you have connected the keyboard to the computer? For PS/2 keyboards the connection at the end of the lead is colored and the port where it needs to be plugged in to should have the same color identification.
If your keyboard is a PS/2 keyboard make sure the computer is shut down before checking the connections.
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